J. Scott Campbell or Jeffery Scott Campbell is an American comic book artist born April 12, 1973 in East Tawas, Michigan, though he has no memories of that city, as his family moved when he was very young to the Denver, Colorado, which he regards as his home. As a child, he was interested in cartoons, rather than comics. He first became interested in comics when, as a teenager, he visited a friend's house, where his friend showed him Uncanny X-Men Annual #10, which featured artwork by Art Adams. J. Scott Campbell began collecting, purchasing books based on the art, not the title, which he says made his collecting habits somewhat difficult at times. In 1989, Campbell, then age fifteen, entered for and won an "Invent the Ultimate Video Game" contest featured in the issue 6 of Nintendo's official magazine, Nintendo Power, whereby submitted contest entries were to consist of drawings and concepts for a video game. Color drawings from "Lockarm," the video game idea he pitched, were published in the magazine as the winning entry. After graduating from high school in Aurora, Colorado, J. Scott Campbell began doing freelance commercial art jobs.

As J. Scott Campbell prepared to show his samples at the 1993 San Diego Comic Con, the series Wild C.A.T.S premiered by Jim Lee's publishing studio, Wildstorm Productions (then called Homage Studios). One issue advertised a talent search for which readers could submit artwork, so Campbell put together a package that included a four-page Wild C.A.T.S story and sent it in. A week and a half later, Jim Lee telephoned Campbell and asked him if he would move to San Diego to work for him. Initially working under the professional name, Jeffery Scott Campbell's first comics work was two pinups for the Homage Studios Swimsuit Special in 1993. His subsequent work for Wildstorm includes spot illustrations in Wild C.A.T.S Sourcebook and Stormwatch.

J. Scott Campbell went on to co-create the teen superhero Team Gen 13, which debuted in Deathmate Black (1993), before going onto to star in their own five-issue miniseries in January 1994. The series was initially co-written by Brandon Choi and Jim Lee, but Campbell became a co-writer with issue #3. The team was eventually given their own regular ongoing series, which debuted in March 1995. Campbell was co-writer on the series until issue #18, and was the regular artist, leaving the book after issue #20 (1997). In 1998, Campbell, together with fellow comics artists Joe Madureira and Humberto Ramos, founded the Cliffhanger imprint as part of Wildstorm Productions.

J. Scott Campbell launched his comic series Danger Girl through this imprint. The story, which followed the adventures of a group of female secret agents, made the most of Campbell's talents drawing well endowed women and dramatic action sequences. The Danger Girl series has since generated a video game for the Sony PlayStation, as well as several comic spin offs in the forms of limited series and one-shots that were drawn by different artists in the American comics industry. Most of these spin-offs featured story outlines from Campbell himself. In August 2005, Campbell published Wildsiderz, which he co-created with his Danger Girl writing partner Andy Hartnell.

In February 2006, the 200th issue of Nintendo Power included a poster featuring prominent Nintendo characters drawn by J. Scott Campbell in his unique art style, along with an interview whereby he recalled his memories of the "Invent the Ultimate Video Game" Contest. That same year, Campbell provided a variant incentive cover for Justice League of America (vol. 2), the first issue of Brad Meltzer's run on the title. In 2007, Campbell illustrated the covers to the Freddy vs. Jason vs. Ash six-issue limited series.In 2016, Marvel pulled from circulation a The Invincible Iron Man variant cover by Campbell after it was criticized as sexualizing the depicted character, a 15 year old Riri Williams.

The pencil work of J. Scott Campbell is done with lead because it strikes a balance between too hard, and therefore not dark enough on the page, and too soft, and therefore prone to smearing and crumbling. When not working on Marvel Comics, he also draws Video Game Covers for Nintendo and Sony Playstation. His Fairy Tale Fantasy prints are highly sought after. The Artwork of J. Scott Campbell is currently credited in 546 separate Comic Book issues.